Nutrition is far more powerful than drugs to improve cognitive performance. We start by looking at cocaine, Adderall, and Ritalin, and show why these drugs cannot possibly hold a candle to nutrition. Optimal nutrition can definitely optimize the function of dopamine, norepinephrine, acetylcholine, histamine, creatine, and the methylation system, and in doing so can simultaneously optimize focus, motivation, sustained attention, and mental flexibility, and methylation, all while eliminating anxiety, depression, and distraction. Yet, popular nutritional cognitive stacks in the nootropic space do not have convincing evidence behind them, and this is probably a result of them trying to do too many things in one capsule. This presentation covers the low-hanging fruit of nutrition for brain power, supplements that help, the importance of individual nutritional optimization, and the central power of finding one's genetic "health super-unlock." For my simple protocol to optimize methylation, see here: https://chrismasterjohnphd.substack.com/p/mthfr-protocol For more detail on finding your own personal genetic health super-unlock, see here: https://chrismasterjohnphd.substack.com/p/unlocking-performance-and-longevity Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.