#406: Peptide OVERLOAD: When Biohacking Backfires (How NOT to Crash Your Mitochondria) With Anthony Castore

Today, I'm joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators. Use code NAT10 for 10% off products at https://alchemiqlabs.com/ Episode Timestamps: Welcome and episode introduction... 00:00:00 Anthony Castore's path from strength coaching to cellular medicine... 00:05:55 Connecting strength training with cellular pathways (AMPK, mTOR)... 00:12:27 Explaining and balancing AMPK and mTOR for performance... 00:13:03 Training strategies: Metabolic, hypertrophy, and neural approaches... 00:18:18 Building a solid foundation: Lifestyle, training, nutrition, peptides... 00:23:04 Assessing recovery capacity and individualizing protocols... 00:26:02 Mitochondrial fission, fusion, and targeted adaptation... 00:29:57 Optimizing muscle gain and fat loss through calories and recovery... 00:31:00 Differentiating bodybuilder vs. longevity approaches... 00:34:44 Integrating peptides and support molecules into routines... 00:40:44 Ketone esters and mitochondrial peptide interventions... 00:41:20 Cautions on stacking and combining interventions... 00:54:04 Lessons learned from overdoing interventions... 01:05:02 Our Amazing Sponsors: Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. BEAM Minerals - Low energy often starts in the mitochondria. Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group