In this episode, we sit down with Dave Friedberg—co-founder of Supergut, co-host of the All-In podcast, and former CEO of The Climate Corporation—to break down the science of the gut microbiome and why fiber—specifically resistant starch—plays such a critical role in optimizing it. Friedberg explains why most common probiotics fail to create lasting change, and introduces resistant starch—a powerful prebiotic—as a more effective way to support long-term gut health. He walks us through how it works, including how beneficial gut bacteria ferment resistant starch to produce short-chain fatty acids like butyrate, which are linked to improved blood sugar regulation, reduced inflammation, and increased production of GLP-1, a hormone that helps regulate appetite. We also dive into his personal philosophy on health, supplementation, and building a successful career—highlighting the non-negotiable importance of sleep and the role curiosity plays in long-term growth.