In this episode of the Gladden Longevity Podcast, Jeff Gladden and Jason Sonners delve into the fascinating world of hyperbaric therapy. Jason shares his personal journey from experiencing a debilitating disc injury to discovering the profound benefits of hyperbaric oxygen therapy. They explore the science behind oxygen's role in cellular function, the therapeutic effects of hypoxia, and the importance of balancing various longevity strategies. The conversation also touches on recent studies regarding telomere length and the potential of hyperbaric therapy to promote cellular health. Finally, they discuss the risks associated with hyperbaric therapy and the importance of gradual exposure to maximize benefits. 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Takeaways · Jason's journey into hyperbaric therapy began with a personal injury. · Hyperbaric therapy can significantly improve oxygen delivery to tissues. · Pressure increases the body's ability to carry oxygen beyond red blood cells. · Hypoxia can trigger beneficial healing pathways in the body. · Balancing various health strategies is crucial for sustainable longevity. · Recent studies show hyperbaric therapy may increase telomere length. · Gradual exposure to hyperbaric therapy can enhance its benefits. · Understanding the risks of hyperbaric therapy is essential for safety. · Hormetic stress can lead to improved health outcomes. · Biology thrives on balance and variety in health practices. Oxygen toxicity can occur with excessive exposure to oxygen. · Hyperbaric therapy sessions are typically shorter than ICU oxygen treatments. · Balancing oxygen levels is crucial for effective therapy. · The minimum effective dose is essential for maximizing benefits. · Glymphatic drainage is important for brain detoxification. · Hyperbaric therapy can be used preventatively for neurological disorders. · Wound healing can be enhanced with hyperbaric therapy pre and post-surgery. · Combining therapies can lead to better outcomes. · Regulatory challenges exist in the growing field of hyperbaric medicine. · Education and training are vital for safe practice in hyperbaric therapy. Chapters 00:00 Introduction to Hyperbaric Therapy 03:02 Personal Journey and Discovery of Hyperbaric Therapy 06:06 Understanding the Science of Oxygen and Pressure 08:55 The Role of Hypoxia and Hormesis in Healing 11:54 Balancing Longevity Strategies 15:08 Telomeres and Longevity: Insights from Recent Studies 18:10 The Importance of Gradual Exposure in Hyperbaric Therapy 21:09 Risks and Considerations in Hyperbaric Therapy 23:07 Understanding Oxygen Toxicity 26:53 Balancing Oxygen Levels for Optimal Health 31:29 The Minimum Effective Dose in Therapy 33:43 Glymphatic Drainage and Brain Health 35:40 Hyperbaric Therapy in Wound Healing 40:49 Future of Hyperbaric Medicine and Regulation To learn more about Dr. Jason Sonners: Website: https://hbotusa.com/ Instagram: https://www.instagram.com/hbotusa Reach out to us at: Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. 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